BIHOCL PureCleanse is a scientifically formulated easy-to-use antimicrobial solution, designed for the advanced treatment of chronic and acute wounds.

Safe, Effective, Thoughtfully Designed Solutions

Treating chronic wounds and burns can be extremely challenging. Now with care plans utilizing the principles of wound bed preparation and T.I.M.E.1,2,3 clinicians are using hypochlorous acid, antimicrobial solutions to effectively reduce chronic wound bed bioburden4,5. In fact, white blood cells produce hypochlorous acid on demand as a first line of natural defense against infection and triggers a cascade of changes that are hallmarks of healing and tissue repair.

With no contraindications for use, hypochlorous acid solutions do not damage healthy cells and tissue as they cleanse and debride the wound bed in preparation for healing 7,8,9,10. As a pure hypochlorous solution, BIHOCL PureCleanse is indicated for the treatment of stage I-IV pressure ulcers, venous insufficiency ulcers, diabetic ulcers, post-surgical wounds, first and second degree burns and minor abrasions6.

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Powerful Antimicrobial

BIHOCL hypochlorous technology is based on the body’s innate cellular response to infection. BIHOCL PureCleanse is a broad spectrum antiseptic which is highly effective against a wide range of microorganisms including gram negative and positive bacteria, antibiotic resistant strains, viruses, fungi, yeasts, and prions6.

Groundbreaking Safety

BIHOCL PureCleanse is non-cytotoxic, non-mutagenic, hypoallergenic, non-pyrogenic, endotoxin free and does not require rinsing6. Our pure and stable hypochlorous acid formulation strikes a unique balance between a powerful antimicrobial and the gentleness of saline.

Simple, Innovative Application

BIHOCL PureCleanse has been designed with healthcare providers and patients in mind. Our easy-to-use irrigation attachments, optimized for solution delivery, provide effective wound bed debridement6.

Biofilm Disruption

Over 90% of chronic wounds contain bacteria and fungi living within a biofilm construct¹¹ and create many challenges in wound care. Ample research has shown that hypochlorous acid solutions such as BIHOCL PureCleanse are effective in disrupting and dismantling complex biofilms through the combined effect of its unique biochemistry and mechanical, pressurized delivery1,13.

Odour Control

The odour associated with non-healing chronic wounds is the result of the microbial breakdown of molecules released in tissue and cellular debris. Hypochlorous acid has been shown to dismantle many of these odour-causing compounds, decreasing VOC output and improving the patient’s quality of life5,14.

BIHOCL PureCleanse Plus irrigation kits for fast, safe, and effective wound cleansing.

Designed for clinicians and NSWOCs to effectively apply BIHOCL PureCleanse at the optimal PSI to cleanse the wound.

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References

Sibbald RG, Williamson D, Orsted HL, et al (2000) Preparing the wound bed: debridement, bacterial balance and moisture balance. Ostomy Wound Manag 46: 14–35

Sibbald RG, Orsted HL, Schultz G, Coutts RN, Keast MD (2003) Preparing the wound bed: focus on infection and inflammation. Ostomy Wound Manag 47: 38–43

Bee, T., et al. (2009). Wound bed preparation – cleansing techniques and solutions: A systematic review. Singapore Nursing Journal, 36(1), 16-22.

Atiyeh, B., et al. (2009). Wound cleansing, topical antiseptics and wound healing. International Wound Journal, 6(6), 420-430.

Williams J, Rasmussen E, Robins L, Varela C, Terry D, Harding, K (forward), The Handbook of HOCl, 2021

Sterasure Inc. data on file, 2022

Andrew M. Jenner AM, Emilio Ruiz J, Dunster C, Halliwell B, Mann GE, and Siow RCM. Vitamin C Protects against hypochlorous acid–induced glutathione depletion and DNA base and protein

Winterbourn CC, Brennan SO. Characterization of the oxidation products of the reaction between reduced glutathione and hypochlorous acid. Biochem J. 1997 Aug 15; 326 (Pt 1):87-92.

Li JX, Pang YZ, Tang CS, Li ZQ. Protective effect of taurine on hypochlorous acid toxicity to nuclear nucleoside triphosphatase in isolated nuclei from rat liver. World J Gastroenterol. 2004;10(5):694-698.

Kearns S, Dawson R Jr. Cytoprotective effect of taurine against hypochlorous acid toxicity to PC12 cells. Adv Exp Med Biol. 2000;483:563-70.

Attinger, C and Wolcott, R, Clinically Addressing Biofilm in Chronic Wounds, Adv in Wound Care, Vol 1, No 3, 2012

Robson MC. Treating chronic wounds with hypochlorous acid disrupts biofilm. Wound Prevention and Management 2020;66 (5):9-10.

Day A, Alkhalil A, Carney BC, Hoffman HN, Moffatt LT, Shupp JW. Disruption of Biofilms and Neutralization of Bacteria Using Hypochlorous Acid Solution: An In Vivo and In Vitro Evaluation. Adv Skin Wound Care 2017 Dec;30(12):543-551.

Ragab, I, Kamal, A, The Effectiveness of Hypochlorous Acid Solution on Healing of Infected Diabetic Foot Ulcers, Journal of Education and Practice, 2017, Vol 8, No 8, pg 58-71